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Literature review
Protein-tyrosine nitration is a post-translational chemical modification process for the highly selective non-enzymatic introduction of a nitro group (-NO 2 ) into the side chain by peroxynitrite (ONOO - ), a short-lived biomolecule generated by the rapid reaction of NO with superoxide radicals in vivo 40,41
The best-fit patients for GLP-1 RAs are those with ASCVD with a high risk of future stroke (e.g., with history of stroke or revascularization, or with evidence of significant artery narrowing)
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
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